Monday, July 29, 2013

Dutch scientists developed a new vaccine for mesothelioma treatment - Health - Cancer

Dutch scientists have developed a novel therapeutic vaccine for the treatment of mesothelioma. Clinical trials using the technology are currently under way. Scientists hope that the research could help patients with this disease Prolong life.

Mesothelioma is a malignant cancer that can start in the cavities of the lungs, the heart, or the abdomen. Pleural mesothelioma can spread to the lungs and invade its inner tissues, but the origin site of the cancer remains the pleura. Pleural mesothelioma is the most common type of mesothelioma and has been studied to a far greater degree than any of the other forms of the disease. Malignant pleural mesothelioma(MPM), originated from pleural mesothelium cell, is an fatal tumor with natual history of only about several months, has showed an increased morbidity recently. Peritoneal mesothelioma, which occurs in the tissue in your abdomen. It usually include abdominal pain and swelling due to a buildup of fluid in the abdomen (ascites). About 50% pleura changes the cancer patient having malignant chest water that the pleura thins out the most common symptom of skin tumour is to breathe hard. Malignant chest water is one of most common symptoms of mesothelioma and directly le ads to shortness of breath ("dyspnea").

The Center scientists made a special vaccine by use of immune cells which are extracted from animals with mesothelioma. The medical community was interested because it offered a chance, potentially, to intervene and prolong life. Scientists said, First, they extract a particular cell from a diseased animal's immune system. Develop it through a special way, These cells are able to identify the mesothelioma cells, and then kill and inhibit mesothelial tumor. These new cells are retransfused into the body. The treatment of mesothelioma to obtain certain effects. if the patients with the early mesothelioma, the tumor has not yet deteriorated to accept appropriate treatment, there may be good results. The treatment of malignant pleural mesothelioma, is still no effective cure methods. Pemetrexed was initially approved in 2004 for treating patients with mesothelioma. It is the only agent for the treatment of malignant pleural mesothelioma(MPM). The early detection of mesotheliom a is critical to the patient's outlook and in determining applicable treatment options.According to a study published in the "Journal of Thoracic Oncology" 5 issue of a study. a drug that is used to treat kidney cancer may enhance the efficacy of chemotherapy for mesothelioma. Temsirolimus, a kinase inhibitor, It can blocks the growth of mammalian target of rapamycin (mTOR) proteins. Order to slow tumor growth. The drug for the treatment of advanced renal cell carcinoma. However, the Austrian researchers found that temsirolimus may also slow down the growth of malignant pleural mesothelioma cells. Mesothelioma is a malignant cancer that can start in the cavities of the lungs, the heart, or the abdomen.





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