Sunday, July 28, 2013

DOE Workers Face Higher Risks for Mesothelioma and Other Cancers - Health - Cancer

Construction workers at four Department of Energy (DOE) nuclear sites have been exposed to asbestos and other dangerous materials that are putting them at significantly higher risk for mesothelioma, lung disease, and other cancers according to a new report published in the American Journal of Industrial Medicine.

Working in construction and other trade jobs at nuclear sites can be risky business. Workers are regularly exposed to a number of cancer-causing substances, including asbestos. Since the mid 1990s, the government has been conducting surveillance programs to determine the health risks faced by workers at four DOE sites: Hanford Nuclear Reservation (Richland, Washington), Oak Ridge Reservation (Oak Ridge, Tennessee), Savannah River Site (Aiken, South Carolina), and the Amchitka site (Alaska).

In past studies, researchers have investigated rates of medical conditions such as respiratory disease and hearing loss among these workers. The current study looked at mortality rates among construction and trade workers. It included nearly 9,000 workers from the four DOE nuclear sites. All of the participants filled out a screening questionnaire, and most of them also had a medical exam. Researchers followed-up on the workers' health status through the end of 2004.

During the study period, 674 of the workers died. Overall, the construction workers had a relatively low mortality compared to the general population, but the authors say this finding could be due to a "health worker effect" (The idea is that, in order to be able to hold a steady job, a person must be generally healthy.)

But when the researchers looked at people in certain types of DOE nuclear site jobs, they saw a spike in death rates. The risk of death was particularly high among asbestos workers/insulators, (93% increased risk), and teamsters (60% higher risk). Construction workers at the nuclear sites faced a much higher than normal risk for lung cancer and mesothelioma, as well as for asbestosis (a lung disease caused by inhaling asbestos fibers). "From our data and other data, asbestos use at the sites was not controlled well, historically," says John M. Dement, PhD, CIH, Professor in the Division of Occupational and Environmental Medicine at Duke University Medical Center. "Clearly there's a need for better controls of asbestos exposures at the sites."

Although he says DOE sites have been making improvements over the past 10 - 15 years to reduce workers' exposures to toxic substances, much of the asbestos that was in place before the EPA's ban in the 1970s has not yet been removed. Because mesothelioma and asbestosis have a long latency period, many of the deaths that are occurring today are actually due to exposures from decades ago. "What we're seeing are the effects of exposure 20 or more years in the past," says Dr. Dement. He expects to eventually see decreases in asbestosis and mesothelioma cases as asbestos use is phased out, although he says these diseases aren't likely to disappear anytime soon.

Dr. Dement hopes that the data generated from his research will help DOE sites design programs to assess potential worker exposures, and then put appropriate preventive programs (using ventilation, respirators, and protective clothing) in place.

The focus is not only on prevention, but also on treating workers who are already at risk. The DOE's surveillance program offers periodic screenings to identify workers who might have been exposed to asbestos and other hazardous substances, and get them the treatment they need. "You're not going to cure them, but you can reduce the impact from a lot of these diseases," says Dr. Dement.





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Saturday, July 27, 2013

Radiotherapy ?Comparable to Chemo? for Mesothelioma - Health - Cancer

A recent study has concluded that palliative radiotherapy produces a response rate in malignant pleural mesothelioma that is comparable to chemotherapy.

A recent analysis of 54 mesothelioma cases at a hospital in Cheltenham, England found that 43 percent of patients who received palliative radiotherapy according to their hospital's policy, responded to the treatment. Most mesothelioma patients are exposed to asbestos fibers at work in industrial settings. Many countries around the world have placed controls on the use of asbestos. However, because of the length of Mesothelioma's latency period, the number of victims around the world many continues to rise.Based on the results of their pre- and post-therapy CT scans, 22 of the 54 mesothelioma patients analyzed experienced a partial response and 1 patient had a complete response. Fifty-seven percent reported some improvement in their symptoms.

In an effort to help determine which mesothelioma patients are most likely to respond to radiotherapy, the research team correlated treatment responses with the European Organisation for Research and Treatment of Cancer (EORTC) prognostic index. Among the patients judged to be in the 'good' prognosis group, 56 percent responded to the radiotherapy, compared to just 7 percent of patients in the 'poor' prognosis group. The EORTC good and poor prognostic mesothelioma groups had survival of 7.1 and 2.1 months respectively from the start of their treatment.

In addition to the EORTC index, survival following radiotherapy treatment was also correlated with each patient's mesothelioma histological subtype, performance status, treatment response and hemoglobin level. Neither tumor volume nor the stage of the patients' cancer was associated with prognosis. The study concluded that palliative radiotherapy for mesothelioma "produces a response rate that is equivalent to chemotherapy" and recommends the EORTC prognostic index as a method of deciding which patients may benefit from this treatment most.

Although the English study was focused solely on the role of radiotherapy, a number of previous studies have found radiotherapy to be most effective when used as part of a multimodality approach to mesothelioma treatment. One such study from the National Cancer Institute in Cairo found that more than 75 percent of patients who had radiation as part of their treatment protocol saw a response (either a decrease in the size of their tumors or in the severity of their symptoms). Recurrence rates were lowest in patients who had high dose hemithorax (one side of the chest) irradiation, a method typically reserved for the healthiest mesothelioma patients.





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Friday, July 26, 2013

The Legal Opition For Mesothelioma Victims - Law

Mesothelioma lawyers have helped many sufferers of this illness get the treatment and compensation they deserve. Mesothelioma is a form of cancer that can quickly cripple or kill a person after it has developed. Many of the symptoms of mesothelioma, such as chest pain, irregular heartbeat, and nausea, are much like symptoms for other kinds of illnesses, so it can be hard to determine whether one has the illness.

Asbestos is the only proven cause of mesothelioma. If one has been exposed to asbestos, one should get tested for mesothelioma. Asbestos used to be used in many everyday consumer products and in many different work settings. In Georgia, the negligence of employers in oil refineries, chemical plants, and other industrial settings caused many persons to develop mesothelioma. Many of the state's Navy veterans were also exposed to asbestos while serving in the mid-to late 20th century. Asbestos was used in ship construction from the 1940s into the 1970s. The illness is fatal, but medical advances can extend the lives of sufferers. However, it is important that individuals who have been exposed to asbestos get tested, even if they have no symptoms of the illness. Early detection and treatment can add a considerable amount of time to one's life.

Most people who develop mesothelioma have worked in jobs where they inhaled asbestos; others were exposed to asbestos dust and fibers in other ways. There is also research suggests which suggests that persons who have washed the clothes of a family member are also at risk of developing mesothelioma. However, there seems to be no association between mesothelioma and tobacco smoking, but using tobacco does increase one's chance of developing other asbestos-related cancers.

A mesothelioma lawsuit can be filed by any individual diagnosed with the illness. However, the best means of succeeding in a legal suit is to prove that the asbestos exposure occurred in the workplace. Mesothelioma lawyers can help victims link their illness to the asbestos exposure by collecting and analyzing their medical and life histories. Litigating such cases can be lengthy and drawn out. But the financial remuneration for those who suffer from mesothelioma can give them the justice they deserve. Such compensation can include Social Security or Veterans benefits.

Unfortunately, many mesothelioma patients do not have a long life expectancy. In the event that a mesothelioma victim dies before a lawsuit can be filed or, once filed, adjudicated, the executor of the victim's estate can carry on the lawsuit as a wrongful death. A Mesothelioma Lawyer South Carolina or a Mesothelioma Lawyer Georgia can guide family member through the intricate legal process of such litigation. In cases in which a family member has been diagnosed with mesothelioma through secondary asbestos exposure, that family member also has the right to file on the original mesothelioma patient's behalf as well as their own. Although a victim of this dreaded illness may not realize the ultimate outcome of the legal proceeding, he or she can put in place the means by which justice can still be achieved.





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Thursday, July 25, 2013

Veterans Benefits & Care for Mesothelioma - Health - Cancer

Based on the details provided by the U.S. Department of Veterans Affairs, there are currently 25 million people who have service the Armed Forces in the United States. Out of these, hundreds of thousands of these living veterans had their share of asbestos exposure during their military service. Veterans account for an estimated 30% of all mesothelioma patients in the country. The extent of treatment for mesothelioma varies depending on their condition. They can apply for Veteran Affairs (VA) benefits for asbestos-related diseases.Veterans Care for Mesothelioma Veterans who are at highest risk of contracting mesothelioma cancer are those who served between 1940s and 1970s. There was a concentration of asbestos exposure during this period as asbestos containing products was not banned in the US until 1975. They were extensively used in the insulation of sleeping quarters, floorings, engines, and boiler rooms. Owing the usage of asbestos products in military, many of them ex posed to the fibers and developed the cancer which was diagnosed at their old age.Veterans and their dependents are offered adequate health care through the Veterans Affairs Department. They can qualify for either benefits or pension, but not both. If they were part of the United States military branch, they will be eligible for benefits provided by the Federal Department of Veterans Affairs (VA). Moreover, all their claims are normally processed at the VA.Benefits for Veterans with Mesothelioma Veteran Affairs help veterans get necessary benefits for mesothelioma like Disability Compensation and VA Health Care. Apart from this, their surviving spouses are also eligible for Dependency and Indemnity Compensation (DIC) they died due to mesothelioma.Disability Compensation is a monthly benefit offered to the veteran victims depending on their disability level which could be anywhere between 0% -100%. Moreover, as mesothelioma cancer is considered as 100% disabling, they will re ceive a monthly benefit which starts at $2,673 per month. This amount would be increased based on the number of people who are dependent on the victim. They can qualify for this compensation if they have been discharged from the military services under any situation other than dishonorable. They need to provide adequate information that they got mesothelioma cancer due to asbestos exposure when they were servicing in the military.Health Care benefits can be provided to veterans that categorize them based on various "priorities". For those with mesothelioma, enrollment to this benefit will be based on whether the cancer is considered "service related" by the VA. Even if they do not qualify "service connected", they can still be part of their income level. The VA uses two different income limits: a National Income Threshold and a Geographical-Adjusted Income Threshold.Dependency and Indemnity Compensation (DIC) is offered to the surviving spouse of the victim with a monthly be nefit of $1154. This is offered provided the victim passed away from a "service-connected" disability. Also it is possible if the victim was getting Disability Compensation from the VA for mesothelioma cancer at the time of his death.Therefore to get all the benefits and care for mesothelioma, the veterans should prove that they were exposed to asbestos while they were in the military.





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Wednesday, July 24, 2013

Nausea Management for Mesothelioma Patients - Health - Diseases and Conditions

Mesothelioma is an aggressive form of cancer that affects the mesothelium, a protective membrane that covers the lungs, heart, and abdomen. The most common treatment for this disease is chemotherapy, which involves ingesting powerful chemicals that attacks the cancerous cells. Unfortunately, while this treatment can be effective, it also has significant side effects for patients, including ongoing and sometimes severe nausea.

Nausea is a serious problem that can contribute to malnutrition, dehydration, and other health problems. It is very important for patients suffering from this side effect to discuss the problem with their doctors. There are many ways to counteract nausea and vomiting; many patients will need to try several different options before deciding on a treatment plan.

Treatment Options

There are several different ways to counteract nausea, although each approach will have different results for different patients. Treatment options include:

Undergoing treatment for mesothelioma is a very challenging experience. However, by maintaining open communication with your doctor, you can learn ways to ease some of the more severe side effects. For more information about coping with this illness, visit the Mesothelioma Resource Center.





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Tuesday, July 23, 2013

Mesothelioma Attorneys: Who are These People? - Health - Cancer

Mesothelioma is a cancerous disease. Its main cause has been proven to be onset by the inhalation of harmful, asbestos fibers. Unlike some other cancerous afflictions, which can be detected at an early stage, symptoms of mesothelioma usually surface at a much later date, commonly having already advanced to an incurable stage. Mesothelioma is commonly treated as an occupational health hazard that primarily afflicts people who work in cement, brick, and insulation manufacturing factories. Since many of these workers have unknowingly put their lives at risk without being properly advised of the necessary precautions or warnings, a patient diagnosed with mesothelioma most often has grounds to file a claim for compensation against the manufacturer(s). This is where mesothelioma attorneys can provide help.

Function of the mesothelioma attorneys:Pursuing a mesothelioma damage case is information intensive. Any attorneys, regardless of their training and experience, suffer from certain limitations. Accurate information concerning the initial period(s) of exposure to asbestos products, and medical documentation of the time of diagnosis of the disease must be furnished to mesothelioma attorneys, who will first study the entire case history and then try to locate missing links and information. Also, documentation must be presented to prove the victims period of employment with a specific manufacturing company. This information is highly relevant concerning the times of exposure and later, of contraction, and constitutes vital evidence, which is critical to filing a successful mesothelioma claim.

There are a variety of other restrictions and qualifications involved in filing such claims that the average person is not usually aware of. Teaming with veteran mesothelioma attorneys with a respectable track record in this type of litigation provides your best chance of pursuing a successful claim. Fortunately, locating a quality lawyer for this type of case from the ranks of reputable attorneys is not exceedingly difficult.

How to select mesothelioma attorneys?Many prestigious private-law institutes provide information on mesothelioma attorneys. Friends and family may suggest a dependable trained professional with whom they are familiar who has previously worked on mesothelioma claims. Much discretion and introspection should be applied while choosing from the many mesothelioma attorneys.

What to look for?

A person should not be inhibited at all in making detailed inquiries during their search for mesothelioma attorneys. One should be confident that the attorney selected is certainly able to perform his job in the best possible manner. Though there is no guarantee of prevailing with a mesothelioma claim, it is best to prepare with knowledgeable mesothelioma attorneys who have demonstrated experience in pursuing the case effectively. However, it must be kept in mind that the time to contact mesothelioma attorneys is limited. Statutory limitations of time for filing a mesothelioma claim begin from the period of the medical reports confirming the patient has contracted this disease.





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Monday, July 22, 2013

pemetrexed plus cisplatin has been used to treat mesothelioma - Health - Diseases and Conditions

Pleural malignant mesothelioma, which affects the tissue that surrounds the lungs and is the most common form of mesothelioma. Pleural malignant mesothelioma originated from pleural mesothelium cell, is an fatal tumor with natual history of only about several months, has showed an increased morbidity recently. One of diffuse malignant mesothelioma of the chest tumor one of the worst prognosis. diffuse malignant mesothelioma is often treated with surgery and chemotherapy. Pemetrexed disodium is the only agent for the treatment of malignant pleural mesothelioma(MPM). Pemetrexed is a targeted therapy drugs. Pemetrexed is a novel anti-neoplastic agent of multitargeted antifolate in the treatment of malignant tumors.Malignant pleural mesothelioma is a rare progressive chest cancer, About 5 percent of tumor of the pleura, the survival rate is 5 - 11 months. The incidence of mesothelioma is related to asbestos exposure. The pathogenesis of malignant mesothelioma is asbestos expos ure. Asbestos fibers are inhaled into the chest, and then Asbestos fibers deposited in the pleural in the form of the spots. Parietal pleura is a disease site. Malignant mesothelioma is a likely worsening of the disease. It is already advanced cancer when the people are diagnosed with mesothelioma. Treatment of surgery, radiotherapy is not very satisfactory. The treatment of malignant pleural mesothelioma is still the main medical treatment, but efficacy and survival is limited.

Pemetrexed is a multitargeted antimetabolite that has shown activity in malignant pleural mesothelioma and NSCLC, which has been approved in more than 70 countries. it is a multi-target folate antimetabolite, mainly inhibit thymidylate synthase (TS), while suppressing the extra folic acid dependent enzymes such as dihydrofolate reductase (DHFR) and GLYCINAMIDE nucleotide switch Formyl enzyme (GARFT). the efficacy of pemetrexed plus cisplatin for patients with malignant pleural mesothelioma. Methods: All 36 patients with malignant pleural mesothelioma were treated by 4 cycles of pemetrexed plus cisplatin. Of the 36 patients there were 24 males and 12 females, the average age was 46.3 2. 6 years. Results: Of all 36 patients, the overall response rate was 55.6 percent, 20 cases received partial remission?no case received complete remission. The major toxicity was nausea and vomit. Only one patient had myelosuppression. Conclusion: Pemetrexed plus cisplatin is a safe and effe ctive regimen in malignant pleural mesothelioma.

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